The image has been miscaptioned and shows Johnson with his former wife, Allegra Mostyn-Owen. His involvement with Maxwell is not known.
A photo purporting to show Ghislaine Maxwell and Boris Johnson has recirculated on social media at several points over the past two years. However, the image has been miscaptioned, as it actually shows the prime minister with his former wife Allegra Mostyn-Owen, not Maxwell. As noted in a 2020 fact check from Snopes, Mostyn-Owen is the daughter of the art historian William Mostyn-Owen and the Italian writer Gaia Servadio. The photograph was taken in 1986 in Oxford, before the pair's marriage in 1987. The marriage ended in 1993.
On November 17, 2021, The Independent reported that the Prime Minister's sister, Rachel Johnson, revealed that Maxwell and her brother were friends while at the University of Oxford. In an article for The Spectator, Johnson wrote that Maxwell flirted with her brother. Boris Johnson has not responded to his sister's comments, and his involvement with Maxwell is not known.