People with Rh-negative blood have a lower risk of COVID-19 illness, but there is no evidence to suggest that they can avoid getting the vaccine.
According to Mayo Clinic, Rhesus (Rh) factor is an inherited protein found on red blood cell surfaces. If one's blood has the protein, they are Rh-positive, and if one lacks it, they are Rh-negative.
As per a study published by the American College of Physicians (ACP) in March 2021, people with type O or Rh−negative blood may be at a slightly lower risk from the new coronavirus. The study was conducted among 225,556 Canadians who were tested for the coronavirus. The risk for a COVID-19 diagnosis was 12% lower, and the risk for severe COVID-19 or death was 13% lower in people with blood group O versus those with A, AB, or B.
A Columbia University study published in November 2020 found evidence for associations between ABO and Rh blood groups and COVID-19. It is found that there is a moderately increased infection prevalence among non-O blood types and Rh-positive individuals. Intubation risk was increased among AB and B types and decreased among A and Rh-negative types.
A study published by National Center for Biotechnology Information (NCBI) stated that the O and Rh blood groups might have a slightly lower risk for coronavirus infection and severe COVID-19 illness. The study was conducted among 2,659,328 persons who had an ABO blood group test from January 2007 to December 2019.
People with type O and Rh- blood groups may have a lower risk of COVID-19, but there is no evidence that they have antibodies that could eliminate the need for vaccination. Medical consultation is advised to consider any vaccination.
The COVID-19 pandemic has given rise to a lot of potentially dangerous misinformation. For reliable advice on COVID-19 including symptoms, prevention and available treatment, please refer to the World Health Organisation or your national healthcare authority.