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Moderna begins the phase-3 clinical trial of the COVID-19 vaccine in the US.

U.S. based pharmaceutical major Moderna has begun a multisite phase-3 clinical trial of the COVID-19 vaccine known as mRNA-1273.

U.S. based pharmaceutical major Moderna has begun a multisite phase-3 clinical trial of the COVID-19 vaccine known as mRNA-1273. The mRNA-1273 was co-developed by the Cambridge, biotechnology company Moderna, Inc. and the National Institute of Allergy and Infectious Diseases (NIAID) part of the NIH. The early-stage clinical testing of the vaccine indicated the investigational mRNA-1273 vaccine to be safe and immunogenic.

The phase-3 clinical trial called the COVE (Coronavirus Efficacy) was meant to decide if the vaccine can prevent symptomatic COVID-19 in adults. The vaccine trial would hire 30,000 people at 89 sites across the country, with half the recipients receiving two shots of the vaccine 28 days apart and the other half receiving placebos.

The trial is designed to evaluate the safety of mRNA-1273 after two doses. The secondary goal aims to study whether the vaccine can prevent severe COVID-19 and seeks to answer if the vaccine can prevent death caused by COVID-19 and whether just one dose can prevent symptomatic COVID-19, among other objectives.

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